Princess Jellyfish follows Tsukimi Kurashita, a shy jellyfish enthusiast living in a Tokyo apartment building with other eccentric, socially awkward women who share a love for niche hobbies. Their peaceful lives are disrupted when a beautiful, fashionable woman named Kuranosuke Koibuchi stumbles into their home—only for Tsukimi to discover that Kuranosuke is actually a man, the son of a wealthy politician, who enjoys cross-dressing. As Kuranosuke becomes a friend and ally, he helps Tsukimi and her housemates fight against developers trying to tear down their building. Readers enjoy the story for its quirky characters, heartwarming themes of friendship and self-acceptance, and the gentle romance that develops between Tsukimi and Kuranosuke, all set against a backdrop of geek culture and fashion.