Girls' Last Tour follows two young girls, Chito and Yuuri, as they travel through a vast, abandoned city and a desolate world after an unnamed war has ended civilization. The story shows them searching for food, fuel, and shelter, encountering remnants of the past and a few other survivors. Readers enjoy the manga for its quiet, melancholic atmosphere, the peaceful contrast between the empty, dangerous world and the characters' gentle friendship, and the thoughtful, wordless moments that make them reflect on life, loss, and finding simple joy in a harsh reality.