BLAME! is a Japanese science fiction manga set in a distant, post-apocalyptic future where a city-sized megastructure known as The City has expanded uncontrollably, consuming the Earth and reaching into space. The story follows a silent, lone cyborg named Killy, who possesses a rare and powerful weapon known as a Gravitational Beam Emitter. He wanders the endless, decaying levels of The City, searching for a human with the "Net Terminal Gene," a genetic trait that would allow access to the lost and corrupted control network of the world. Most of the surviving inhabitants are hostile "Safeguard" AI constructs or degenerate human factions. Readers enjoy BLAME! for its immense, hauntingly beautiful and claustrophobic atmosphere, its minimalist storytelling that relies heavily on visual world-building, and the relentless, lonely journey of Killy. The manga is celebrated for Tsutomu Nihei's distinctive, gritty art style, which conveys a sense of scale, mystery, and desolation unlike any other work.